DIACOMIT® treatment should be undertaken under the supervision of a medical doctor who is knowledgeable about Dravet Syndrome. All initiation, change or modification of antiepileptic treatment must only be made with the approval of the medical practitioner who regularly follows the patient. If you should have any questions regarding treatments, you should feel free to ask this doctor.
Interactions between DIACOMIT® and valproate are considered as moderate.
In case the patient experiences side effects, a weekly 30% reduction of the daily dose of valproate should be done. This reduction may be renewed until disappearance of the side effect.
Click to launch animation
The average dose of valproate is generally around 15mg/kg/day (please refer to DIACOMIT® scientific discussion)
In general the most common side effects encountered when associating valproate with DIACOMIT® are: anorexia, appetite loss, weight loss.
For references, please access “Using DIACOMIT” through the Bibliography part located in Resources tab.